Browse Data
U2OS Cell Map
- The U2OS cell map
- The U2OS MuSIC map contains 5,147 proteins organized into 275 subsystems. This global map of subcellular structure was generated by integrating immunofluorescent images with biophysical interactions derived from AP-MS.
- U2OS cell map subsystems
- The 275 subsystems in the U2OS cell map in tabular format. Each row represents a subsystem in the map with information on enrichment analyses, subsystem genes, and links to subnetworks. The second tab describes the information in each column.
- U2OS immunofluorescent images
- There are 20,660 immunofluorescent images for 10,348 proteins in the U2OS cell line. This file contains a link to every RGB image used in the U2OS cell map and the corresponding gene name and antibody.
- U2OS biophysical interactions
- The U2OS biophysical interaction network contains 36,842 edges between 7,543 unique proteins. This interaction network was derived from affinity purification-mass spectrometry experiments. MS raw files are available via MassIVE with the identifier MSV000097168.
- U2OS size exclusion chromatography data
- There are three technical replicates of SEC-MS data. These files contain the protein quantification results for each replicate. MS raw files are available via Proteome Xchange with the identifier PXD052362.
- 3D Structural models
- AlphaFold-Multimer 3D structural models for protein pairs in U2OS cell map assemblies.